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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Shi-Qi Zhao

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Open access Sep 2026

Gray matter atrophy mediates the association between cerebral hypometabolism and cognitive impairment in Alzheimer’s disease

Objective Alzheimer’s disease (AD) is characterized by amyloid deposition, brain hypometabolism, gray matter atrophy and cognitive decline, yet their causal interactions are poorly defined. This multimodal PET/MRI study explored regional gray matter volume (GMV) loss and glucose hypometabolism in AD patients, and clari...

Shi-Qi Zhao, Jian-Wen Chen, Pei-Xue Li et al. · 0 citations

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