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Shi-Qi Cai

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Review Open access Aug 2026

Functional genomics–guided design of CAR-T and CAR-NK therapies in hematological malignancies: aligning cellular engineering with immune escape and microenvironmental resistance

Future CAR-T and CAR-NK development should link each modification to a measurable resistance mechanism, a feasible biomarker, and a clinically testable benefit, before resistance-matched cellular immunotherapy can be broadly integrated into clinical practice.

Shi-Qi Cai, Yang Tan, Qian Yang et al. · 0 citations

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