Author

Sheng Xu

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Sep 2026

DDR1 sustains ferroptosis resistance in pancreatic ductal adenocarcinoma via SLC40A1-mediated iron homeostasis.

Findings identify DDR1 as a key regulator of iron metabolism and ferroptosis in PDAC, suggesting that dual targeting of DDR1 and ferroptosis represents a promising therapeutic strategy.

Chao Song, Lu-Ting Zhang, Sheng Xu et al. · Oncogene · 0 citations

Jul 2026

ARID1A Stimulates Notch-TLL1 Signaling to Induce Cancer-Associated Fibroblast Activation and Intrahepatic Cholangiocarcinoma Development.

It is demonstrated that ARID1A, a core component of the SWI/SNF protein complex, is upregulated in ICC and plays an oncogenic role and acarbose is revealed as a potential precision therapy for ARID1A-high ICC patients.

Sheng Xu, Jing-Yi Huang, Kang Wang et al. · Cancer Research · 0 citations