Review
Open access
Sep 2026
IL-10’s contextual role in cytotoxic antitumor immunity: evidence, controversies, and therapeutic translation
Interleukin-10 (IL-10) is classically defined as a potent anti-inflammatory cytokine that protects tissues by constraining myeloid activation and limiting inflammatory cytokine production. Yet, accumulating evidence indicates that, in defined contexts, IL-10 can also promote antitumor immunity by enhancing the fitness...
Min-Chuan Zhang, Qi-Jing Li, Kong-Peng Lam et al.
· Frontiers in Immunology · 0 citations