Shen Li

Untargeted plasma metabolomics identifies metabolite signatures associated with suicidality status in chronic schizophrenia

Uric acid-associated psychopathology in first-episode drug-naïve schizophrenia stratified by depressive symptoms.

The UA-psychopathology association was exclusive to FEDN-SCZ patients with depressive symptoms, while non-depression patients were characterized by glucose and energy dysregulation.

Metabolic biomarkers of treatment-resistant schizophrenia and cognitive correlates: insights from a machine learning.

Sex-stratified associations between depressive symptoms and cognitive impairment in treatment-resistant vs. non-resistant schizophrenia.

Integrated proteomics and network pharmacology reveal autophagy-lysosomal regulation underlying sulforaphane-mediated neuroprotection in Alzheimer's disease.

SFN pretreatment protected against Aβ-induced neuronal injury in this in vitro model and was associated with modulation of autophagy-lysosomal and apoptosis-related pathways, a systems-level framework for understanding the multitarget neuroprotective actions of SFN.

Metabolomics analysis reveals BMI-related metabolic characteristics in schizophrenia patients.

Distinct metabolic profiles characterize BMI heterogeneity in SCZ and are differentially associated with cognitive impairment and negative symptoms.

Altered right amygdala-prefrontal connectivity is associated with symptom severity in major depressive disorder: An exploratory analysis of anxiety subgroups.

The findings identify disrupted right amygdala-MFG connectivity as a potential neural correlate of symptom heterogeneity in MDD, particularly in patients with anxiety symptoms.