Distinct structural architectures of mushroom (1 → 3),(1 → 6)-β-D-glucans are associated with different biological responses in breast cancer cells.
Two distinct (1 → 3),(1 → 6)-β-D-glucans, designated GlcEtPp and GlcEtSn-300, were purified from an alkaline extract of the mushroom Lactarius quieticolor and structurally characterized by GC-MS, HPSEC-MALS-RI, and NMR spectroscopy. Structural analysis revealed marked differences in side-chain organization, with GlcEtP...