Shashank Nadimpalli

Sphingolipid Regulation of Genome Stability: Stress Signaling, Chromatin Control, and Organelle Dysfunction

Sphingolipid metabolism has emerged as a regulatory interface between lipid homeostasis, organelle stress, and genome maintenance. Although sphingolipids are essential structural components of cellular membranes, specific metabolites also function as bioactive mediators that shape cellular responses to genotoxic stress...