BACKGROUND
Glioblastoma (GBM) is a highly aggressive brain tumor for which cell-free DNA (cfDNA) has shown promise as a minimally invasive biomarker, yet the biological processes governing cfDNA release and composition in GBM remain incompletely understood.
METHODS
We investigated cfDNA release dynamics, fragmentatio...
Sharvari Mankame, Angad Beniwal, M. Dufault et al.· Neuro-Oncology· 0 citations
Background Pediatric and adult brain tumors, including glioblastoma, astrocytoma, ependymoma, and medulloblastoma, remain associated with poor prognosis despite advances in surgery, radiation, and chemotherapy. Therapeutic resistance, tumor heterogeneity, and treatment-related toxicity highlight the need for clinically...
Margarita Gutova, Eric Ma, H. Natri et al.· bioRxiv· 0 citations
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