Sharvan Sehrawat

An anti-Galectin-3 intrabody improves primary and memory response of antigen-specific CD8+ T cells during viral infection

Genetic ablation approaches are routinely used to establish gene function, but these are not beyond limitations. The intracellularly expressed camelid single-domain antibodies (sdAbs), or nanobodies, can specifically disrupt molecular interactions and, therefore, help ascertain their role in the process of cellular dif...