Review
Open access
Jul 2026
Metabolic reprogramming of cancer associated fibroblasts informs stromal heterogeneity and therapeutic targeting.
The tumor microenvironment (TME) refers to the non-malignant cellular and stromal components present within tumors, which play critical roles in cancer initiation, progression, metastasis, and therapeutic response. Among the diverse cellular constituents of the TME, cancer-associated fibroblasts (CAFs) represent a key...
Haicheng Ma, Hengxiao Lu, Zhenyu Zhang et al.
· Discover Oncology · 1 citation