Review
Open access
Jul 2026
Temporal interference stimulation: A new paradigm for non-invasive deep brain stimulation-mechanistic insights, clinical advances, and future directions.
This review provides a comprehensive synthesis of TI's mechanistic foundations, safety profiles, and therapeutic trajectory, while critically discussing the integration of closed-loop systems, multi-target paradigms, and patient-specific optimization as the next frontiers in non-invasive deep brain stimulation.
Wenjiang Wang, Missey Florian, Chenxi Ling et al.
· Translational Psychiatry · 0 citations