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Shaogeng Tang

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Open access Aug 2026

Humanized Anti-PD-1 Antibodies Generated Using The Conditional Kernel-Elastic Autoencoder

A machine learning-based approach to evolve new anti-PD-1 antibodies within a chemically informed latent space using a conditional kernel-elastic autoencoder (CKEA) between nivolumab and pembrolizumab to preserve favorable therapeutic features while exploring variants with different potency.

Yuanjun Shi, Haote Li, Pulan Liu et al. · 0 citations

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