Open access
Aug 2026
Discovery of Highly Efficacious CRBN-Based KRAS Degraders Targeting Cancers with KRAS G12D and G12V Mutations
CW-10201 represents a promising KRASG12D and KRASG12V degrader for extensive evaluation and optimization for the treatment of human cancers.
Chang-Wei Wang, Prithwish Ghosh, Shi-Cheng Jin et al.
· Journal of Medicinal Chemist... · 0 citations