Shao-Jie Zhu

Integrative ATAC-seq and RNA-seq reveal chromatin remodeling as a hub of immune, oxidative, and metabolic reprogramming under heat and hypoxia stress in Apostichopus japonicus.

The sea cucumber Apostichopus japonicus holds significant economic importance in China's marine aquaculture. However, climate change-particularly extreme summer temperatures and hypoxia-has caused substantial economic losses in major production regions. These stressors impair the physiological, immunological, and survi...