HIV-1 Vpr: a multifunctional accessory protein with potential contributions to AIDS pathogenesis and persistence
Human immunodeficiency virus type 1 (HIV-1) infection can progress to acquired immune deficiency syndrome (AIDS), which is characterized by a rapid decline in CD4 + T lymphocyte counts, severe impairment of host immune competence, and recurrent opportunistic infections. Over the past four decades, HIV infection has...