Author

Shao-Dong Chen

2 papers indexed here

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Review Open access Sep 2026

Lipid-Droplet Remodeling in Hepatic Stellate Cells in Liver Fibrosis: An Evidence-Tiered Synthesis of Lipophagy, Retinoid Metabolism, and Organelle Crosstalk

In quiescent hepatic stellate cells (HSCs), lipid droplets (LDs) constitute specialized retinoid-rich storage organelles. Upon hepatic injury, various characteristics of LDs—including their abundance, size, composition, retinoid storage capacity, mobilization dynamics, metabolic flux, and associated cell signaling path...

Zhe Li, Xin-Yi Kwan, Qi Liu et al. · Current Issues in Molecular... · 0 citations

Open access Sep 2026

Geniposide alleviates CCl4-induced liver fibrosis: Potential involvement of the PERK-CHOP signaling pathway

Geniposide is the primary active component of the cycloether terpenoid glycoside class extracted from the traditional Chinese medicinal herb Gardenia jasminoides, and it possesses multiple pharmacological activities, including neuroprotection, antidiabetic effects and hepatoprotection. It has been shown that endoplasmi...

Yue Yu, Xin-Yi Kwan, Hui-Qing Liang et al. · Biomedical Reports · 0 citations