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Shang-Gao Liao

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Open access Sep 2026

Ent-abietane diterpenoid Enantiomers from Euphorbia helioscopia inhibits liver fibrosis via suppressing the TGF-β1/smad pathway

Despite abietane diterpenoids exhibit various biological activities, their anti-fibrotic activity has rarely been investigated. In the study, 19 diterpenoids (twelve abietanes and seven other types) were isolated from E. helioscopia , comprising five undescribed ent -abietane type diterpenoids ( 1a , 1b , and...

Li Jiang, Qian Wang, Jun-Yan Ran et al. · 0 citations
Jul 2026

Hepatoprotective effects of Persicaria capitata against alcoholic liver injury by regulating the gut-liver axis via PI3K-Akt and TLR4/NF-κB signaling pathways.

ETHNOPHARMACOLOGICAL RELEVANCE Persicaria capitata, a vital Miao medicine, is traditionally employed to "clear heat and promote diuresis" and "detoxify". In traditional theory, alcoholic liver injury (ALI) is categorized as a "Damp-Heat accumulation" syndrome, often manifesting as damp-heat jaundice. The traditional ap...

Lu Hu, Jin Li, Ya-Xin Yang et al. · 0 citations

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