Shalini Andersson

In Vitro Exploration of Antisense and Splice-Switching Oligonucleotide Multimers Using an Engineered Peptide Scaffold

Antisense oligonucleotides (ASOs) are potent therapeutics that enable precise RNA modulation. However, efficient delivery to tissues and cell types remains a major challenge. Multimerization, linking multiple ASOs to form large constructs, represents a promising strategy to explore delivery and pharmacokinetics modul...