Development and Evaluation of a Prolonged-Release Imeglimin Hydrochloride Matrix Tablet using Hydrophilic-Hydrophobic Polymer Blends
Objective: The present work was aimed at designing and optimizing a prolonged-release matrix tablet of Imeglimin hydrochloride (500 mg) employing binary polymer combinations of hydroxypropyl methylcellulose (HPMC) K100M and Carbopol 940P as rate-controlling polymers for sustained antihyperglycemic action over 12 hours,...