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Author

Shai Kaluski-Kopatch

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2 papers indexed here

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Oct 2026

The divergent 3D genome landscapes of aging and neurodegenerative mouse models.

Chromatin structure is essential for gene regulation and genome stability, as neurons must preserve their 3D genome organization throughout life. This structure gradually deteriorates with aging and is further disrupted in neurodegenerative diseases. To investigate whether aging and neurodegeneration share early chroma...

E. Kashuk, Dmitrii Smirnov, Ekaterina Eremenko et al. · 0 citations
#protein folding Open access Sep 2026

HSPD1 promotes neuroblastoma by augmenting MYCN expression

It is shown that HSPD1 depletion in MYCN-amplified NB cells led to reduced mitochondrial translation, MYCN expression, and tumorigenesis in vitro and in vivo and establishes HSPD1 as a promising target for the treatment of MYCN-amplified NB.

Shatha S. Alassam, Dinesh Babu Manikandan, Hila Ben-David et al. · 0 citations

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