Shachi P. Vyas

Translational control of T cell expansion and autoimmune responses by a non-conventional RNA binding protein 2252845

Naïve CD4+ T cells respond to antigenic stimulus and rapidly transition into active state by intensifying clonal expansion. To meet the bioenergetic demand for this energy-intensive process, CD4+ T cells modulate their transcriptional and translational regulatory mechanisms and fuel profound increase in protein p...