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Hierarchically and Temporally Distinct Ca2+ Signaling Across Thalamic Nuclei During Nociceptive Stimulation
ABSTRACT Background The thalamus serves as a critical relay hub for transmitting peripheral nociceptive information to the cerebral cortex and plays a central role in the sensory, motor, affective, and cognitive dimensions of pain processing. However, the dynamic response patterns of distinct thalamic nuclei during sti...