Author

Sha Cao

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Meta-analysis Open access Sep 2026

Conserved hepatic RNA signatures across multiple cohorts reveal novel mechanistic clues for advanced fibrosis in human MASLD

Background: Fibrosis development in patients with metabolic dysfunction–associated steatotic liver disease (MASLD) is a key indicator of disease progression and clinical outcome. Bulk and single-cell transcriptomics on human tissue have advanced understanding of fibrosis progression, but interstudy heterogeneity and li...

Jessica L. Maiers, Tie-Bing Liang, Tingbo Guo et al. · Hepatology Communications · 0 citations

Sep 2026

The post-transcriptional regulator HuR promotes immune evasion in pancreatic ductal adenocarcinoma.

Overall, it is found that the post-transcriptional regulator HuR facilitates immune evasion in PDAC by constraining T-cell function, identifying HuR blockade as a promising therapeutic strategy in combination with immunotherapies.

Yi-Fei Guo, Jennifer M. Finan, Alexandra Q. Bartlett et al. · Cancer immunology research · 0 citations

Open access Aug 2026

Deep-learning-enabled multi-omics analyses for prediction of future metastasis in cancer

EmitGCL is developed, a deep-learning framework to predict metastasis and related biomarkers using cancer single-cell sequencing data, enabling and validating the discovery of occult metastases and breast cancer metastasis biomarkers.

Xiaoying Wang, Maoteng Duan, Anthony J. Snyder et al. · Nature Communications · 0 citations