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Author

Şeyma Ateşoğlu

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Aug 2026

Short and efficient synthesis of the natural triterpenoids α- and β-amyrins with detailed in silico screening and in vitro anticancer evaluation against breast and prostate cancer cells.

Overall, α- and β-amyrins, particularly α-amyrin, represent promising lead compounds targeting ERα and AR for the development of therapies against hormone-dependent cancers.

Halil Şenol, Salih Tuncay, Şeyma Ateşoğlu et al. · 0 citations
Aug 2026

Rational design of thiazolidine-2,4-dione-integrated combretastatin A-4 analogues as potent and selective tubulin-targeting agents for triple-negative breast cancer.

The present study identifies compounds 2 and 3 as promising lead candidate that combines potent and selective antiproliferative activity, strong tubulin polymerization inhibition, and favorable binding characteristics compared with paclitaxel.

F. S. Tokalı, Şeyma Ateşoğlu, Pelin Tokalı et al. · 1 citation

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