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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

Seth B. Herzon

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2 papers indexed here

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Open access Sep 2026

Targeting O6-methylguanine-DNA methyltransferase deficiency in preclinical models of extracranial human cancers with a tumor-selective DNA modifying agent

Temozolomide (TMZ) is an established therapy for gliomas with silencing of the DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT) but is hindered by the frequent development of resistance via loss of mismatch repair (MMR) proteins. To overcome this resistance, a novel 2-fluoroethylating agent, KL-50, was...

R. Sundaram, Spenser S. Johnson, Siddhant P. Bhoir et al. · 0 citations
Sep 2026

A Platform for the Production of Pleuromutilin and Core-Modified Derivatives

The structural complexity of pleuromutilin antibiotics has limited efforts to define aspects of the natural scaffold that are required for antibacterial activity. Here, we present a scalable synthetic platform that provides access to novel core-modified bicyclic pleuromutilins (BPs) and the natural tricyclic pleuromu...

Zhan-Hao Liang, Q. Yang, Antonio Ramkissoon et al. · 0 citations

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