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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Sergio Vulterini

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Review Sep 2026

Estrogen insensitivity syndrome: the 'Upside Down' of ESR1 mutations.

The estrogen receptor α (ERα) is a central regulator of 17β-estradiol (E2)-dependent physiological processes in reproductive and non-reproductive tissues. Deregulation of ERα signaling underlies distinct human pathologies, including breast cancer (BC) and the rare genetic disorder called estrogen insensitivity syndrome...

Claudia Bellucci, M. Cipolletti, Sergio Vulterini et al. · 0 citations

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