Aug 2026
Astragalus polysaccharides ameliorate irinotecan-induced gut toxicity by regulating gut microbiota and suppressing the MAPK signaling.
Findings suggest that APS, the key active fraction of AM against IGT, mitigate IGT by modulating microbiota-metabolite-MAPK axis, offering novel mechanistic insight for the ethnopharmacological use of AM to mitigate chemotherapy-induced intestinal toxicity.
Bolin Wu, Chenyang Zhou, Chuting Xu et al.
· Journal of Ethnopharmacology · 0 citations