Dermatofibrosarcoma protuberans (DFSP) is a borderline malignant, locally highly aggressive, but rarely metastasizing fibroblastic skin tumor. This review aims to provide a comprehensive, evidence-based overview of DFSP, encompassing its molecular pathogenesis, diagnostic workup, clinical variants, and current treatmen...
Julia Lisanne Kalthöfer, Selma Ugurel· Cancer Advances· 0 citations
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy, yet the basis of variable patient responses remains unclear. We assemble a longitudinal single-cell RNA sequencing atlas of 441 samples from 241 patients across ten cancer entities to map treatment-associated remodeling of the tumor immune microenviro...
Zhongyang Lin, Mitalee Chandra, Nalini Srinivas et al.· Cancer Cell· 1 citation
Sweat gland carcinomas (SGC) are rare tumors frequently driven by somatic mutations. More than 20 distinct SGC entities are recognized, many of which exhibit overlapping histopathological features, making accurate diagnosis challenging. This review provides a comprehensive overview of SGC entities and summarizes curren...
Lara Racz, A. Böer-Auer, F. Meier et al.· European Journal of Cancer· 0 citations
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