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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Sébastien Lemieux

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2 papers indexed here

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Open access Sep 2026

A biological-response compound representation allows chemical perturbation prediction across cell lines

Accurately predicting cellular responses to drugs remains a challenge with the potential to reduce experimental screening costs and accelerate drug discovery. Current computational approaches represent compounds through chemical structures, which carry little information regarding their activity within biological syste...

Léa Kaufmann, Lola Le Breton, E. Carraz-Billat et al. · 0 citations
Oct 2026

EZH2 Inhibition Induces a Metabolic Stress Response Sensitizing Triple-Negative Breast Cancer to Glutaminase Targeting.

EZH2, the catalytic subunit of the histone methyltransferase complex PRC2, is overexpressed and associated with poor prognosis in triple-negative breast cancer (TNBC). Although EZH2 inhibition significantly alters chromatin landscapes and gene expression, it has limited impact on the growth of TNBC models, suggesting a...

Lucas Porras, M. Carrière, Ann-Sophie Gironne et al. · 0 citations

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