Is complete really complete? Prognostic divergence of pathological complete response after FLOT versus CROSS in esophageal adenocarcinoma.
OBJECTIVE To review whether pathological complete response (pCR) in esophageal adenocarcinoma (AC) may be regime-dependent and to outline its implications for surveillance, adjuvant therapy and trial design. BACKGROUND ESOPEC established perioperative FLOT as superior to preoperative CROSS for survival and distant di...