Open access
Aug 2026
Pharmacological Inhibition of Small Extracellular Vesicle Secretion by ALK5i SD‐208 via Lysosomal Rerouting of CD63+ Compartments
It is demonstrated that SD‐208 diverts CD63+ multivesicular bodies (MVBs) from a secretory fate toward lysosomal degradation and uncovers a new regulatory link between lysosomal pathways and EV trafficking.
Rahul Sanwlani, Georgina H. Thompson, Kyle Bramich et al.
· Journal of Extracellular Ves... · 0 citations