Open access
Sep 2026
Anti-CD40L prevents meningeal B cell aggregates and mitigates progressive autoimmune encephalomyelitis.
Compartmentalized inflammation within the CNS is considered to drive progressive immunopathology in multiple sclerosis (MS) independently of relapses. Meningeal tertiary lymphoid structures (TLS) represent an immune niche associated with histological signs of immunopathology, including demyelination in the adjacent CNS...
Sofia Tyystjärvi, Diego Ruiz Navarro, Leni-Mihaela Kulisch et al.
· Brain : a journal of neurolo... · 0 citations