Open access
Sep 2026
Modular mRNA cocktail enables synergistic activation of antigen-specific T cells for cancer immunotherapy
Abstract mRNA-based therapeutics have demonstrated notable success in SARS-CoV-2 vaccines and are emerging in cancer immunotherapy. However, conventional mRNA cancer vaccines are limited in part by the low immunogenicity of tumor-associated and neoantigens. We addressed this limitation by formulating a modular, liposom...
Toan Van Le, Shota Imai, Iriya Fujitsuka et al.
· Oncoimmunology · 0 citations