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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Sasan Shabani

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Review Open access Sep 2026

Targeting p66Shc by natural-derived and synthetic compounds in organ toxicity

The p66Shc protein functions as a cellular stress sensor that facilitates the elimination of irreversibly damaged cells under physiological conditions. However, during chronic stress, this pathway becomes maladaptive, contributing to progressive tissue degeneration. The present study reviews the involvement of p66S...

Fatemeh Yarmohammadi, Sasan Shabani, G. Karimi · 0 citations

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