Design, Characterization, and Anti-Cancer Activity Evaluation of Palbociclib-Loaded Nanosponges in A498 and Mcf-7 Cell Models
Objective: To formulate and evaluate palbociclib-loaded nanosponges (PB-NSPs) as a controlled drug delivery system to improve the solubility, stability, and release behavior of palbociclib for cancer therapy. Methods: PB-NSPs were prepared using β-cyclodextrin (β-CD) and characterized for particle size, zeta potential,...