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Sarah Leuchtenberg

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Open access Oct 2026

PDS5A restricts SYN4-dependent long-range chromatin contacts to shape TAD-like chromatin architecture in Arabidopsis.

Three-dimensional genome folding in vertebrates, such as the formation of topologically associating domains (TADs), depends on cohesin-mediated loop extrusion, yet its regulation in plants remains unresolved. Using Hi-C and Micro-C, here we show that Arabidopsis cohesin regulator PDS5A is a key modulator of chromatin l...

Sofia Tzourtzou, Zhi-Dan Wang, Sarah Leuchtenberg et al. · 0 citations

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