The human kidney contains highly specialized cell populations. Despite numerous single-cell and single-nucleus transcriptomics studies, differences in cohorts, technologies, analytical pipelines, and annotation frameworks have limited the ability to define consensus kidney cell states, identify disease-associated popul...
Konstantinos Stasinos, Han-Chen Wang, A. Predeus et al.· bioRxiv· 0 citations
Invariant natural killer T (iNKT) cells are unconventional ɑβ T cells that respond to lipid-based antigens. They play a vital role in response to infections and are involved in diseases such as allergic asthma and cancer. Despite clear immunological roles across multiple diseases, remarkably few tools exist to study iN...
Alyssa H Cull, James L C Che, Sandy MacDonald et al.· Journal of Immunology· 0 citations
This framework provides an important mapping of GRNs involved in thymic T cell differentiation, particularly focusing on Tregs and will serve as an important basis for understanding Treg biology and improving Treg-based therapies.
B. Lee, Ioannis Sarropoulos, Yoonseo Park et al.· Journal of Immunology· 0 citations
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