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Sara Ladak

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Open access Oct 2026

Adoption and practice variation of DPYD genotyping prior to fluoropyrimidine therapy at two Canadian cancer centres.

528 Background: Fluoropyrimidines are widely used in the treatment of solid malignancies. Variants in the dihydropyrimidine dehydrogenase ( DPYD ) gene increase the risk of severe fluoropyrimidine-associated toxicity. Following guidance from Ontario Health (Cancer Care Ontario) recommending DPYD genotyping...

Sara Ladak, L. Thanabalachandran, Alisia Chen et al. · 0 citations

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