Sara Farshineh Saei

Recognition of Single-Strand-Duplex Junctions in RNA Using Peptide Nucleic Acids That Form Watson-Crick and Hoogsteen Hydrogen Bond.

Sequence-specific recognition of complex, folded RNA structures is a highly desirable yet formidable goal. The present study explored nucleobase-modified peptide nucleic acids (PNAs) as ligands that bind and recognize junctions between single- and double-stranded RNA via Watson-Crick and Hoogsteen hydrogen bonding, res...