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Sara E Cahill

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Open access Jul 2026

MARCO is an IFN-restricted immunometabolic decoy LPS receptor 2308885

The mechanism by which MARCO facilitates LPS clearance to limit activation of the non-canonical inflammasome is defined, which shows that activation of the non-canonical inflammasome is preceded by a priming step by which type I interferon (IFN) suppresses MARCO expression on TRMs to allow for optimal recognition of LPS and activation of caspase-11.

Shriram Ramani, Sara E Cahill, M. Finnegan et al. · 0 citations

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