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Author

Sara Ancel

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Review Sep 2026

Strengthening muscle for healthy ageing: innovative treatments for sarcopenia.

The recent surge in clinical trials combining weight loss-inducing GLP1RA therapies with drugs that preserve muscle tissue suggests that treatments that promote both healthspan and lifespan, or 'healthy ageing', are on the horizon.

Sara Ancel, E. Le Moal, Yu-Xin Wang et al. · 0 citations
Open access Jul 2026

Sulfotransferase signaling sustains fibroblast identity and antagonizes therapeutic cardiac reprogramming

It is shown that the sulfotransferase CHST7 stabilizes fibroblast fate via CD44/JUNB signalling, and that its inhibition enhances cardiac reprogramming and improves heart repair, and defines a sulfotransferase-dependent barrier to cell fate conversion with therapeutic implications for heart regeneration.

Michaela R. Romero, S. Murphy, Yu-Zhu Chang et al. · 0 citations

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