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Author

Sara Alrawashdeh

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2 papers indexed here

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Review Open access Oct 2026

Overview of screening assays used to evaluate PROTACs for cancer treatment.

Proteolysis-targeting chimeras (PROTACs) are promising anticancer agents, but optimizing them requires screening strategies that go beyond simple target-degradation readouts. This review provides an overview of assays for evaluating anticancer PROTACs and classifies them by their role in the degradation pathway, includ...

Raghd Obidat, Jazmin Reyes-Martinez, Sara Alrawashdeh et al. · 0 citations
Review Open access Oct 2026

New insights into FOX proteins in cancer.

Forkhead box (FOX) proteins are transcription factors whose dysregulation drives tumor initiation, metastasis, and therapy resistance, yet their direction of effect is determined by cellular context rather than by their conserved DNA-binding domain. Applying explicit criteria across all 44 human members, we find contex...

Sara Alrawashdeh, Gazia Buzaakuk, Raghd Obidat et al. · 0 citations

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