Open access
Aug 2026
BACE2 Promotes Bladder Cancer Chemoresistance Through Proteolytic Activation of JAG1‐Notch Signaling
A novel BACE2‐JAG1‐Notch signaling axis that contributes to bladder cancer chemoresistance is defined and identified as a potential prognostic biomarker and a therapeutically actionable target to improve clinical outcomes in this disease.
Zekun Li, Sanxiang Li, Zhenyu Liu et al.
· Cancer Innovation · 0 citations