Sandrine Compeyrot-Lacassagne

Whole exome sequencing of paediatric patients with Cogan’s syndrome to identify monogenic mimics

Abstract Objectives Cogan’s syndrome (CS) is a rare variable vessel vasculitis, describing sensorineural hearing loss (SNHL), inflammatory ocular disease and vestibular dysfunction. We hypothesized that within paediatric-onset (p)CS, a proportion would have monogenic disease, either autoinflammatory and/or associated w...