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Author

Sandra Delgado

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Open access Oct 2026

Glycosylation Encodes Selective Galectin Recognition and Signaling by Osteopontin

Post-translational modifications critically regulate extracellular molecular recognition, yet their roles in intrinsically disordered proteins remain poorly defined. Here, we integrate glycoproteomics, NMR, and cellular assays to reveal how glycosylation shapes the interaction network of osteopontin (OPN), a highly g...

I. A. Bermejo, D. del Balzo, M. Azkargorta et al. · 0 citations
Open access Aug 2026

The protein sequence modulates terminal GalNAc incorporation during N-glycan biosynthesis.

The factors governing protein-specific N-glycosylation remain incompletely understood despite extensive knowledge of the biosynthetic machinery involved in glycan assembly. In particular, the contribution of the protein sequence itself to the final glycosylation pattern has received comparatively little attention. Here...

Luca Unione, Sandra Delgado, Jesús Jiménez-Barbero et al. · 0 citations

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