Sep 2026
Dimethyl fumarate ameliorates amyloid-beta generated cognitive deficits by inhibiting RIPK1/RIPK3/MLKL necroptosis signalling in rats.
The results indicate the cognitive improvement and neuroprotective effects of DMF in Aβ1-42 CE model by modulating the necroptosis signalling and suggest that the selective targeting of necroptosis process may open new treatment avenues for AD.
Sandeep Guin, Aditi Jangli, Manoj P. Dandekar
· International Immunopharmaco... · 0 citations