Open access
Aug 2026
Evolutionary implications of phenotype switching for growth and survival of tumors in stochastic environments
A mathematical model of tumor growth under fluctuating conditions with stochastic phenotypic epithelial-mesenchymal switch as the main mechanism of adaptation is developed, and non-trivial evolutionary outcomes are revealed, depending on the relative time scales of the underlying processes.
Sanasar G. Babajanyan, Y. Wolf, R. Canevarolo et al.
· bioRxiv · 0 citations