This review synthesizes the mechanistic insights, engineering strategies, clinical evidence, and emerging platforms, including in vivo lentiviral CAR-T generation, that define the current landscape, and proposes a tiered framework for next-generation solid tumor CAR-T development, while explicitly acknowledging the limitations and unknowns that persist.
Samuel Obiosa Onyekweli, Gloria Osayamen Omoruyi, C. O. Akintayo et al.· Oncoscience· 0 citations
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