Author

Samuel N. Emerson

2 papers indexed here

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Review Oct 2026

Histone-modifying Enzymes as Therapeutic Targets in Glioma: Biological Rationale and Translational Findings.

Histone-modifying enzymes have emerged as therapeutic targets in glioma, particularly H3K27M-altered diffuse midline glioma. This article reviews the biological rationale for targeting these enzymes and summarizes the current preclinical and clinical evidence for histone deacetylase, methyltransferase, and demethylase...

Briana Santo, A. K. Ahmed, Samuel N. Emerson · Hematology/Oncology Clinics... · 0 citations

Open access Aug 2026

‘An NF2-wildtype malignant meningioma cell line for basic and translational science’

Background Meningiomas are the most common primary nervous system neoplasm in adults. There are few good cellular models, especially of high grade/malignant meningiomas, to use to identify new therapeutic agents and treatment regimens. The widely available, partially characterized, NF2-wildtype (NF2wt) Grade 3 malignan...

Perry Chien, Brendan F. Kohrn, Megan M. Nguyen et al. · bioRxiv · 0 citations