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Author

Samuel A. Myers

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2 papers indexed here

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Open access Sep 2026

IL-27 induces a cytotoxic state in CD4+ T cells distinct from the Th1 lineage

CD4+ cytotoxic T lymphocytes (CD4-CTLs) are understudied immune mediators with ambiguous origins. Despite expressing RUNX3, granzyme B (GZMB), and perforin (PRF1), CD4-CTLs are frequently classified as Th1 extensions due to shared interferon-γ (IFNγ) and T-BET expression. Here, we identify interleukin-27 (IL-27) as a i...

M. Matias, R. Marrocco, Kyle Magro et al. · 0 citations
Open access Aug 2026

A molecular switch for coordinating kinesin and dynein transport of mitochondrial cargo

A regulatory helix in the mitochondrial adaptor protein (TRAK) that mediates switching between kinesin- and dynein-driven transport is identified and reveals a molecular mechanism for coordinating the directional transport of mitochondria in response to intracellular signals.

C. Gladkova, Maria G Paez-Segala, W. Grant et al. · 2 citations

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